Session 06: Safety Assessments for Dietary Supplements and Herbal Products[Symposium Program （Session）]
According to the WHO report, Traditional and Complementary Medicine (T&CM) is an important health resource in many countries, especially in Asian countries. T&CM products include herbs, herbal preparations, and herbal products. There is an increasing global interest in the use of botanicals or derivative products because people believe that such products as “natural” may be beneficial to health. However, the complex chemical nature of herbal dietary supplements makes it difficult to evaluate their efficacy and safety. The reported adverse effects have raised concerns of public health risks regarding the concentration, composition, and individual contaminants of herbal supplements. The WHO Traditional Medicine Strategy has announced to strengthen quality assurance, safety, proper use, and effectiveness of T&CM; and the International Agency for Research on Cancer (IARC) has assessed the carcinogenicity of some herbal products, and part of them are classified as Group 2B (possibly carcinogenic to humans). Since little has been done to determine the potential risks associated with prolonged or high-dose use of herbal products, toxicological profiles of many herbal products that are currently on the market need to be scientifically evaluated. In this proposed symposium, safety issues about the herbal products will be discussed by scientists from different countries.
President:
NO.:1
The serious adverse reactions due to the adulteration of herbal products with chemicals and synthetic drugs
NO.:2
ecNGS reveals increased hepatocarcinogenic risk of aristolochic acid under steatohepatitis inflammation
NO.:3
The balance between safety and efficacy for the approvement of dietary supplements in Korea
NO.:4
Malaysia’s safety framework for herbal and dietary products
Session 12: The Science, Application and Management in Risk Assessment[Symposium Program （Session）]
In the past several years, many new regulations and standards have been issued for the safety/risk assessment of chemicals and consumer goods in China, such as multiple guidelines for cosmetic safety assessment issued by the National Medical Products Administration (NMPA), the technical guidelines for environmental and health hazard assessment of chemical substances (trial) issued by the Ministry of Environmental Protection, etc. Meanwhile, new approaches like NAMs, NGRA and IATA have been developed and gradually transformed for safety assessment. From regulatory agencies, higher attention has been paid to the safety of chemicals and products, and higher requirements have been put forward for safety assessors. Therefore, to advance science and better enable the practice of risk assessment in China, we will conduct a symposium plus roundtable discussion afterwards for theme of “the science, application and management in risk assessment”, which will invite both international and domestic speakers to share and exchange the challenge and opportunity together. Hopefully this will strengthen the confidence of risk assessment practice in China.
NO.:1
The future is now: Implementing animal-free safety assessment for cosmetics
NO.:2
The development, challenge and opportunity of risk assessment in China
NO.:3
Use of NAMs to refine and strengthen SAR read-across
NO.:4
Discussion on the practice of safety assessment for cosmetics under regulatory framework in China
